rapid diagnosis of spontaneous bacterial peritonitis using leukocyte esterase dipstick testing
نویسندگان
چکیده
background: ascitic fluid infection is presumptively diagnosed when the fluid polymorph nuclear (pmn) concentration equals or exceeds 250 cells /mic,l. the leukocyte esterase (le) test has been shown to be a good predictor of the presence of pmns in urine and other body fluids. this study examines of value of multistix 8sg dipstick test for rapid diagnosis of infected ascitic fluid. materials and methods: seventy three ascitic fluid samples were evaluated by pmn count and le dipstick testing. le dipstick values of small or greater were considered positive. for each samples the le test result was compared to the corresponding pmn count. results: from 73 total patient (mean age: 55.1) they were 38 female (mean age: 46.4) & 35 male (mean age: 64.4). the causes of cirrhosis were hbv infection (39.7%), hcv infection (12.3%), autoimmune hepatitis (9.6%), cryptogenic (15%), other (4%) and under evaluation (13%).the most finding in sbp negative group was asymptomatic (79%) butâ abdominal pain (77%) in sbp positive group. eight of ten le positive samples has pmn≥250 cells/mic,l while eight of nine samples with pmn≥250 cells/mic,l were also le positive.of 63 le negative samples, 62 were also negative by pmn count. sixty two of 64 samples with pmn‹250 cells/mic,l had negative le test. the sensitivity and specificity of the le test for detecting ascitic fluid pmn≥250 cells/mic,l were 88.8% (95% ci: 52-100%) and 97% (95% ci: 89-100%) respectively with a positive predictive value of 80%, a negative predictive value of 98.5%, and an accuracy of 95%. conclusion: the multistix leukocyte esterase test is useful for prompt detection of an elevated ascitic fluid pmn count, and recommended as a conveniant new method for the rapid diagnosis of infected ascitic fluid.
منابع مشابه
Diagnostic validity of leukocyte esterase dipstick test for diagnosis of spontaneous bacterial peritonitis in cirrhotic patients.
BACKGROUND Spontaneous bacterial peritonitis (SBP) is defined as an ascitic fluid infection without an evident intra-abdominal surgically treatable source. Spontaneous bacterial peritonitis (SBP) is one of the severe complications in patients with cirrhosis and ascites. Without early antibiotic treatment, this complication is associated with high mortality rate, so early diagnosis and treatment...
متن کاملEvaluation of leucocyte esterase reagent strip test for the rapid bedside diagnosis of spontaneous bacterial peritonitis.
BACKGROUND Spontaneous bacterial peritonitis (SBP) is a common serious complication of cirrhosis, and carries a high morbidity and mortality. Rapid diagnosis and prompt treatment of this condition may improve survival of such patients. OBJECTIVE To validate the diagnostic efficacy of a leukocyte esterase reagent (LER) strip test for rapid, bedside diagnosis of SBP. METHODS We prospectively ...
متن کاملretracted article: diagnostic value of leukocyte esterase test strip reagents for rapid clinical diagnosis of spontaneous bacterial peritonitis in patients admitted to hospital emergency departments in iran
conclusions the use of leukocyte esterase urine dipstick test can be a quick and easy method in early diagnosis of sbp to start the treatment until preparation of sbp-cell count results. results in this study, 100 patients with ascites due to cirrhosis, with an average age of 38.9 ± 6.54 years were evaluated. twenty cases had positive results, of whom 17 cases were also detected based on the st...
متن کاملRapid diagnosis of spontaneous bacterial peritonitis using leukocyte esterase reagent strips in emergency department: uri-quick clini-10SG® vs. Multistix 10SG®.
BACKGROUND AND AIM Bacterial peritonitis (SBP) is the most frequent infection in patients with cirrhosis causing significant mortality. Delay in SBP diagnosis is a serious problem. The aim of this study was to evaluate the diagnostic yield of Uri-Quick Clini-10SG® vs. Multistix 10SG® reagent strips in an Emergency Department. MATERIAL AND METHODS A prospective study of consecutive patients wi...
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عنوان ژورنال:
گوارشجلد ۱۱، شماره ۴، صفحات ۲۵۵-۰
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